中文名称非唑奈坦中文同义词非唑奈坦;化合物FEZOLINETANT;(R)-(4-氟苯基)(8-甲基-3-(3-甲基-1,2,4-噻二唑-5-基)-5,6-二氢-[1,2,4]三唑并[4,3-A]吡嗪-7(8H)-基)甲酮;非佐奈坦英文名称Fezolinetant英文同义词FEZOLINETANT;ESN-364;ESN364;ESN364;ESN-364;Methanone,[(8R)-5,6-dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)-;Inhibitor,NeurokininReceptor,ESN364,Tachykininreceptor,ESN364,Fezolinetant,inhibit,NKreceptor;(R)-(4-fluorophenyl)(8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-Chemicalbookyl)methanone;Fexolinetant;FezolinetantCAS号1629229-37-3分子式C16H15FN6OS分子量358.39EINECS号相关类别医药原料药;医药原料;贝尔卡主打;APIS;APIMol文件1629229-37-3.mol结构式非唑奈坦性质沸点623.0±65.0°C(Predicted)密度1.56±0.1g/cm3(Predicted)储存条件Storeat-20°C溶解度DMSO:20.0(最大浓度mg/mL);55.8(最大浓度mM)形态固体酸度系数(pKa)-0.28±0.40(Predicted)颜色白色至黄色InChIInChI=1S/C16H15FN6OS/c1-9-13-19-20-14(15-18-10(2)21-25-15)23(13)8-7-22(9)16(24)11-3-5-12(17)6-4-11/h3-6,9H,7-8H2,1-2H3/t9-/m1/s1InChIKeyPPSNFPASKFYPMN-SECBINFHSA-NSMILESC(N1CCN2C(C3SN=C(C)N=3)=NN=C2[C@H]1C)(C1=CC=C(F)C=C1)=O |