中文名称醋酸酯化丁二酸氢酯化的纤维素-2-羟基丙基甲基醚中文同义词羟丙基甲基纤维素乙酸酯/琥珀酸酯;醋酸酯化丁二酸氢酯化的纤维素-2-羟基丙基甲基醚;醋酸琥珀羟丙甲纤维素USP标准品英文名称HYDROXYPROPYLMETHYLCELLULOSEACETATESUCCINATE英文同义词Cellulose,2-hydroxypropylmethylehter,acetatehydrogenbutanedioate;aceticacid,methanol,propane-1,2-diol,succinicacid;HYDROXYPROPYLMETHYLCELLULOSEACETATESUCCINATE,(HPMCAS);HyproMelloseAcetateSuccinate;HYDROXYPROPYLMETHYLCELLULOSEACETATESUCCINATE;HPMCAS;HypromelloseAcetateSuccinate(100mg);HydroxypropylMethylcelluloseacetatesuccinateJPECAS号71138-97-1分子式C10H22O9分子量0EINECS号相关类别中间体;医药原料;有机化工原料;化工原料;化工中间体;有机原料Mol文件MolFile结构式醋酸酯化丁二酸氢酯化的纤维素-2-羟基丙基甲基醚性质熔点>203°C(dec.)储存条件Hygroscopic,-20°CFreezer,Underinertatmosphere溶解度Practicallyinsolubleinethanol(95%),hexane,unbufferedwater,andxylene.Ontheadditionofacetone,oramixtureofethanol(95%)anddichlorometChemicalbookhane(1:1),aclearorturbidviscoussolutionisproduced.HypromelloseacetatesuccinatealsoformsaclearorturbidsolutioninbuffersofpHgreaterthan4.5withtherankorderofsolubilityforthevariousgradesincreasingwiththeratioofacetyloversuccinoylsubstitution.TheexactpHvalueatwhichthepolymerstartstoswellanddissolvedependsonthebuffertypeandionicstrength,althoughtherankorderforthedifferentgradesisindependentofthebufferused.Nosolventhasbeenfoundtocompletelydissolvehypromelloseacetatesuccinatepolymer;theresultingclearorturbidsolutionssignificantlyscatterlightinbothstaticanddynamiclightscatteringexperiments,indicatingthatthepolymermayexistascolloidsoraggregates.ThedataiscollatedfromtheShin-EtsuChemicalCo.Ltdandtheresearchworkoftheauthors(RChen,BCHancock,andRMShanker).形态固体颜色白色至类白色稳定性吸湿性LogP-0.591(est) |