中文名称CS-2620中文同义词化合物GSK5182;(Z)-4-(1-(4-(2-(二甲基氨基)乙氧基)苯基)-5-羟基-2-苯基戊-1-烯-1-基)苯酚英文名称GSK5182英文同义词GSK5182;CS-2620;(Z)-4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-5-hydroxy-2-phenylpent-1-en-1-yl)phenol;(E/Z)-GSK5182;Benzenebutanol,δ-[[4-[2-(dimethylamino)ethoxy]phenyl](4-hydroxyphenyl)methylene]-,(δZ)-;4-[(Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-5-hydroxy-2-phenylpent-1-enyl]phenol;inhibit,GSK-5182,GSK5182,ReactiveOxygenSpecies,GSK5182,EstrogenChemicalbookReceptor/ERR,Inhibitor;(E/Z)GSK5182,(E/Z)GSK5182,(E/Z)-GSK-5182CAS号877387-37-6分子式C27H31NO3分子量417.55EINECS号相关类别Mol文件877387-37-6.mol结构式CS-2620性质沸点567.6±50.0°C(Predicted)密度1.132±0.06g/cm3(Predicted)溶解度DMSO:54.5(最大浓度mg/mL);130.52(最大浓度mM)乙醇:84.0(最大浓度mg/mL);201.17(最大浓度mM)形态固体酸度系数(pKa)10.27±0.15(Predicted)颜色米白色至浅黄色CS-2620用途与合成方法生物活性GSK5182是一种4-hydroxytamoxifen类似物,是estrogen-relatedreceptorγ(ERRγ)的一种特定的反向激动剂,可抑制促炎性细胞因子诱导的分解代谢因子。靶点TargetValueERRγ() |