中山几何生物科技有限公司
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产品名称： AZD-8330(ARRY-424704) Cas No.： 869357-68-6 规格:： 价格： 1元/ 发布日期:： 2016-07-28
AZD8330 is an orally active, selective MEK inhibitor with an IC50 of 7 nM.
AZD8330 potently and strongly inhibits MEK 1/2. AZD8330 has no inhibitory activity against over 200 other kinases including at concentrations up to 10 μM. AZD8330 demonstrates sub-nanomolar potency in mechanistic (pERK) and low to sub-nanomolar potency in functional (proliferation) assays in MEK 1/2 inhibitor sensitive cell lines.
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